New Blood Tests Might Detect Allergies in Dogs

Allergies are a common problem from which many dogs suffer. These allergies are triggered by a variety of things and can cause a wide range of symptoms, that range from mild to severe. Atopic dermatitis is a condition that inflames the skin and leads to severe itching. This is usually caused by some form of allergy. It is often difficult to diagnose and the tests for allergies do not always have definitive results. This is an area that researchers have been working on to try and shorten the process of diagnosis. They now believe it is possible to use biomarkers in the blood to identify atopic dermatitis, says Dogster. They are also continuing to research the possibility of using stem cell therapy to reduce the inflammation of atopic dermatitis.

Dogs suffer from allergies when their immune system overreacts to something and releases histamines and antibodies. They can have allergies to various triggers, such as foods, pollens, dust, smoke, flea bites, and grass. One of the most common ways that an allergy affects a dog is skin-related symptoms. For many years, there have been a variety of treatments available for veterinarians to prescribe to dogs suffering from atopic dermatitis. As research into this field continues, there are continually new treatments for this condition. So, treatment of the condition is not particularly problematic. The bigger issue is diagnosing this condition in the first instance.

According to Veterinary News, it is often a lengthy process to diagnose atopic dermatitis. It can involve many stages, including eliminating potential allergens, reviewing patient history, conducting diet trials, allergy testing, and clinical examination. Now, a company that manufactures cell therapies and a research team from the Western University of Health Sciences have collaborated on research into using biomarkers in the blood to identify atopic dermatitis. Their findings were published in the journal PLOS ONE.

The researchers have found that there are biomarkers in the blood that can identify atopic dermatitis. Not only does this give an instant diagnosis, but it also gives guidance for the best form of treatment for the underlying cause of the inflammation. This will make a significant difference to the way that vets diagnose atopic dermatitis and it will save a lot of time in reaching the diagnosis and beginning treatment. Those who worked on this study have now extended their research to look into the potential for stem cell therapies as a treatment for atopic dermatitis. Their preclinical study is investigating whether it is possible to use mesenchymal stem cells as a treatment for canine atopic dermatitis. The aim of this study is to determine whether this form of treatment can lead to a reduction in inflammation and scratching.

It is scheduled for the preclinical study to come to an end by the end of 2019. Depending on the findings of this study, the team could potentially continue with a clinical trial. The aim of the clinical trial will be to develop an FDA-approved stem cell therapy to use as a treatment for atopic dermatitis. Compared to the treatments already available for this condition, it is possible that stem cell therapy could offer the most effective treatment. The impact of the research findings has the potential to achieve a far wider impact than simply the treatment of canine atopic dermatitis. The company linked to the study, VetCell Therapeutics, would like to use the findings of the clinical trials to move forward with a human therapy for dermatitis. To do this, they would use the same principles as with the current research. They will do this under the guidance of PrimeGen Global, which is their parent company.

The team from the Western University of Health Sciences and VetCell Therapeutics are not the only research team who are currently working on potential treatments for canine atopic dermatitis, as there are several other ongoing studies in this field. One of the groups who are also studying this topic is Kindred Biosciences. This company has been conducting studies into antibodies for the treatment of atopic dermatitis in dogs. They recently announced that their study had positive results.

Their pilot field study involved using 62 client-owned dogs, all of which suffer from atopic dermatitis. Some dogs were given the antibodies, while other dogs were given a placebo. The antibody they have identified and used in the study is KIND-016, which is a fully caninized, high-affinity monoclonal antibody. The aim was to find out if the antibody they had identified would effectively reduce inflammation and itching for dogs suffering from canine atopic dermatitis.

The study lasted for four weeks, and the levels of itching were measured using a Pruritus Visual Analog Scale {PVAS). Levels of itching were measured at various points throughout the study. The researchers found that there was some reduction of itching in as little as four hours after the antibody was delivered. After one week, the treatment success rate was around 70 percent. In the fourth week, the group that had received the antibody showed a 60 percent success rate in relation to the reduction in itching.

Positive results such as this have huge implications in terms of finding effective treatments for canine conditions. However, the impact extends much further as it is possible that these studies could influence research into treatments for humans and inspire further research into the uses of stem cell therapies.

This is an area of science and medicine that is currently attracting lots of attention, and those involved in these fields have made huge progress in recent years. It is likely that studies relating to stem cell therapies for both veterinary and human purposes will continue in future years, and that scientists in this field will continue to make significant progress. Therefore, research into stem cell therapies will remain at the forefront of medical research and play an important role in future medical innovations and advancements.



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